Studies & Treatments
Ophthalmology
The Stem Cell Ophthalmology Treatment Study II (SCOTS 2) is the world’s largest clinical trial using autologous bone marrow-derived stem cells to explore potential therapies for vision loss. Conducted with scientific rigor and adherence to ethical standards, SCOTS 2 has produced five peer-reviewed publications in leading medical journals, with two more under review and additional studies underway. Our research represents a significant step forward in the field of regenerative ophthalmology.
We focus on patients experiencing vision loss due to optic nerve or retinal diseases, and have treated over 47 different conditions, including glaucoma, NAION, optic atrophy, hereditary optic neuropathies, age-related macular degeneration, diabetic retinopathies, Stargardt disease, retinitis pigmentosa, and other inherited retinal and macular disorders. Our clinical experience and data collection are aimed at advancing both patient outcomes and scientific understanding.
SCOTS 2 is not a replacement for standard medical care, but a complementary option for those who have completed all routine treatments. We encourage patients to first pursue established therapies and consult with their ophthalmologists. Our mission is to provide scientifically grounded hope where conventional treatments have reached their limits.
Neurology
The Neurologic Stem Cell Treatment Study (NEST) is the largest clinical study of neurologic conditions using autologous (patient-derived) bone marrow stem cells. We address a range of neurologic disorders, including Chronic Stroke (CVA), Parkinson’s Disease, Multiple Sclerosis (RR, PP, PR, SP), Traumatic Brain Injury (TBI), and Peripheral Neuropathy (including Diabetic Neuropathy).
All conditions are reviewed on a case-by-case basis. Treatment typically involves BMSC administration intravenously and intranasally.
Spinal Cord Injury
The Stem Cell Spinal Cord Injury Exoskeleton & Virtual Reality study (SciExVR) is the most advanced spinal cord injury trial using autologous bone marrow stem cells. Our protocol delivers BMSCs via six targeted paraspinal injections—at, above, and below the injury site—followed by intravenous and intranasal delivery.
Depending on individual needs and equipment availability, patients may undergo standard physical therapy, exoskeleton-assisted training, or virtual reality-enhanced rehabilitation.
Our objective is to restore sensory, autonomic, and motor function to the greatest extent possible.
Autism Spectrum Disorder
The Alzheimer’s, Autism, Cognitive Impairment Stem Cell Treatment Study (ACIST) is an IRB-approved, NIH-registered clinical study (NCT 3724136) investigating the use of autologous (patient-derived) bone marrow stem cells in treating Autism Spectrum Disorder (ASD) in adults aged 18 and over.
Participants undergo evaluation using standardized ASD assessments, including the Autism Spectrum Quotient (AQ). Existing preclinical and clinical research suggests potential benefits of BMSCs in various neurologic conditions. Notably, Duke University Medical Center has conducted related studies using autologous umbilical cord blood in pediatric ASD patients.
ACIST does not replace standard care. All participants are expected to have completed conventional treatments before enrollment.
Alzheimer's & Dementias
Alzheimer’s Disease and related dementias profoundly impact both patients and caregivers. The Alzheimer’s, Autism, Cognitive Impairment Stem Cell Treatment Study (ACIST) is an IRB-approved, NIH-registered clinical trial (NCT 3724136) exploring the use of autologous bone marrow-derived stem cells (BMSCs) in these conditions.
Candidates are first assessed using the Mini-Mental State Examination (MMSE) and must score within the dementia range to qualify. Eligible diagnoses may include Alzheimer’s Disease, Lewy Body Dementia, Multi-Infarct Dementia, CADASIL, and others.
Treatment arms may involve BMSCs delivered intravenously, intranasally, or in combination with Near-Infrared Light (NIR) therapy. Both approaches are supported by emerging evidence in the scientific literature.
Anti-aging
The pursuit of longevity and the preservation of bodily function have long been human goals. With advancements in regenerative medicine and stem cell therapy, we are now making unprecedented progress.
Ongoing research in proteomics (the study of cellular proteins) and metabolomics (the analysis of metabolic byproducts) is uncovering key factors that influence cellular aging and rejuvenation. Autologous bone marrow-derived stem cells (BMSCs), which naturally respond to injury and tissue repair, may play a vital role in supporting youthful function.
Our focus is on promoting recovery and preservation of integumentary (skin) and muscular systems, aiming to counteract age-related decline where possible.
Next Steps...
For more information, please reach out.