The NEST Study: Innovation in Regenerative Neurology
The Neurologic Stem Cell Treatment Study (NEST) is an NIH-registered human clinical study dedicated to evaluating the impact of cellular therapy on the central and peripheral nervous systems. At MD Stem Cells, we provide patients with access to investigational treatments designed to explore the potential of neuroregeneration.
Our study focuses on the use of autologous bone-marrow–derived stem cells (BMSCs) to address neuroinflammation and support the repair of damaged neural tissues in patients where conventional medical interventions may have limited effects.
Neurologic Conditions Supported
The NEST study is currently evaluating the role of regenerative medicine across several categories of neurologic conditions:
Movement Disorders:
Parkinson’s Disease, Progressive Supranuclear Palsy (PSP), and Dystonia.-
Autoimmune & Demyelinating Diseases:
Multiple Sclerosis (MS) and Neuromyelitis Optica. -
Injury & Vascular Conditions:
Stroke recovery (CVA), Traumatic Brain Injury (TBI), and Spinal Cord Injury. -
Cognitive & Peripheral Disorders:
Alzheimer’s, early-stage dementia, and various forms of Peripheral Neuropathy.
How the NEST Study Works: Our Dual-Delivery Approach
The NEST protocol is distinguished by its sophisticated delivery methods, designed to ensure that concentrated stem cells reach the nervous system effectively.
The Procedure Breakdown
Bone Marrow Harvest
A minimally invasive aspiration is performed by a physician to collect a small amount of the patient’s own bone marrow.
Cellular Processing
Using FDA-cleared technology, the marrow is processed to isolate a high concentration of the patient’s live stem cells.
Dual-Delivery Method: * Intravenous (IV) Infusion
Concentrated cells are returned to the bloodstream to target systemic inflammation and travel to damaged tissues.
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Intranasal (IN) Application:
Cells are delivered via a specialized intranasal route. Research suggests this allows cells to bypass the blood-brain barrier by following the olfactory and trigeminal nerve pathways directly to the brain.
Potential Study Observations
While the NEST study is investigational, participants and researchers have documented various observations that contribute to our growing body of knowledge in regenerative neurology. These include:
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Neuroprotection:
Potential slowing of disease progression through cellular support. -
Reduced Neuroinflammation:
Calming the immune response that often accelerates neurologic decline. -
Functional Improvements:
Some participants report enhancements in gait, balance, fine motor coordination, and cognitive clarity.
Investigational Note: These observations are variable and patient-specific. As a clinical study, results are not guaranteed and are used to further scientific understanding.
Why Choose MD Stem Cells for Neurologic Care?
Decade of Leadership
One of the world’s most experienced teams in autologous bone marrow protocols.
Scientific Accountability
Our study is NIH-registered, ensuring transparent data collection and oversight.
Patient Safety
By using autologous (your own) cells, we eliminate the risk of tissue rejection or the ethical concerns of donor-derived materials.
Compassionate Expertise
Our physicians guide you through every step, prioritizing your safety and clear communication.
The Patient Journey: A Simple 3-Day Process
Evaluation
A comprehensive medical review to determine your eligibility for the SCOTS 2 or NEST protocols.
Procedure
A minimally invasive, physician-directed procedure using your own bone marrow-derived stem cells.
Follow-Up
Ongoing monitoring and support as part of our commitment to the clinical study's data and your wellbeing.
Check Your Eligibility
Enrollment in the NEST study requires a documented neurologic diagnosis and a review of your recent medical imaging (MRI or CT scans) and specialist reports. If you are seeking a new approach to neurologic health, we invite you to begin our formal review process.
Medical Disclaimer: Stem cell treatments offered through SCOTS 2 are investigational and conducted within NIH-registered clinical studies. These treatments are not FDA-approved standard of care. Outcomes vary and are not guaranteed.
Our Clinical Support Path
Discover how our NIH-registered NEST study connects patients with innovative regenerative techniques for neurologic conditions. Reach out to learn more about your options.